ICMR BULLETIN VOL. 26-No.-9-SEPTEMBER-1996
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- ICMR BULLETIN VOL. 26-No.-9-SEPTEMBER-1996
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ISSN 0377-4SU0
Vol. 26, No. 9
September, 1996
PROSPECTS OF USING, MONOMOLECULAR SURFACE FILMS IN
MOSQUITO CONTROL
The appearance of acquired resistance in larvae of
vector mosquitoes to most conventional larvicides stimu
lated a search fbr finding alternative methods .of mosquito
control1. One such method is to physically kill mosquito
immatures by suffocating them and prevent ovipositing fe
males from laying eggs on the water surfoce. Studies during
the last decade yielded new group of compounds called
monomolecular organic surface films These surface film
forming agents bring about changes i耳 the surface tension
of water thereby disrupting the normal development and
behaviour of immature stages of mosquitoes2. Since they kill
mosquito larve and pupae physically, chances of-resistant
development in mosquitoes are remote3,4. Srious forms of
monolayer surface films have been proposed as potentially
useful in the control of mosquitoes2,5'11.
In the past, attempts were made to combine the positive
aspects of surface active films, biocides and insecticides fbr
vector control11'15 (VCRC unpublished data). In the present
article an attempt has been made to review the role of
monomolecular surface films alone or in combination with
other larvicides and biocides in vector control.
Physical and Biocontrol Properties of Monomolecular
Surface Films against Mosquitoes
Aliphatic alcohols
Long chain fatty alcohols (C12-C20 chain length) when
sprayed over the water surface, form a monomolecular
layer16. Continuous surface layer of lauryl alcohol interfered
with respiration and led to asphyxia and a 100 per cent
inhibition in adult emergence in Culex quinquefasciatus}1.
Monolayer formed by long carbon chain aliphatic alcohols
such as 1- decanol, 1- undecanol and 1- docecanol caused
cent per cent mortality in the immatures of Aedes aegypti
andAe. scuteHaris at the dosages of 5-7 1/hectare18. Monolayers of certain synthetic surfactants have been reported to
kill anopheline larvae within 24 h2,3,19.
Initially, long chain aliphatic alcohols act as an irritant
and finally cause death of the larvae by breaking down lipid
composition of the cellular structures. The critical properties
that determine the body penetrating capabilities of these
alcohols are liphophilicity, molecular geometry and dehy
drating properties20.
・
Lower carbon chain alcohols (benzyl alcohol and 2octanol) were found to be ineffective due to volatility. They
tend to evaporate before they have a chance to cause damage
to the tissues ofthe mosquitoes. On the other hand, very long
carbon chain alcohols (1-tetra decanol, 1-hexa decanol and
1-octa decanol) were effective only at very high dosages and
were therefore not suitable. These are most solid, wax-like
substances at room temperature requiring solvent (hexane)
before application. However, blending of 1-didecanol and 1tetra decanol was found to be effective against all stages of
mosquitoes17,21.
Table L Effect of monomolecular surface films on mosquito immatures.
Species
Dosage
(1/ha)
Habitat
Source
POE(4)LE, POE(2)LE & SMO 75/2EB
An. quadrimaculatus
0.41： .
Laboratory and simulated
field conditions
White & Garrett (1977)2
White et al (1978)
*
9
Arosurf MSF
Cx. quinquefasciatus
Cx. ni^ripalpus
Ponds of sewage treatment system
33
Levy et al (1980)5
Ae. taeniorhynchus
Salt marsh
*
3.0-4.5
Levy et al (1981)7
Pso. Columbia^
Pso. ciliatab^
Cx. quinquefasciatus
Cx. nigripalpus
Ponds of sewage treatment system
and rain water pools
*
2.0-4.5
Levy et al (1982)9
An. quadrimaculatus
An. crucians
Standing paludal ponds
*
3.0-4.0
Levy et al (1982)10
Cx. tarsalis
Cx. pens
Clear non vegetated ponds and dairy
waste water lagoons
6.9-9.43b
Mulla et al (1983)1
Ae. nigromaculis
Ae. ntelanimon
Cx. tarsalis
Cx. quinquefasciatus
Experimental plots
*
2.5-10.0
Takahashi et al (1984)4
Cx. quinquefasciatus
Ae. aegypti
An. stephensi
Stagnant water bodies
11.2C
Das et al (1986)M
Co. perturbansF
Cattail marsh
4.67"
Kenny & Ruber (1992)26
Effective duration
:
*
(a) three days; (b) 14 days; (c) two to 12 weeks; (d) seven days.
•- > 90% mortality of larvae, pupae and emerging adults.
A-Psorophora Columbia; 3-Psorophora ciliata\ C-Coquillattidia perturbans.
Superscripts numbers are the si.,nos. in the reference list
ArosurfR MSF
The usefulness of ArosurPMSF (ISA-20E, ArosurP
66-E2) [polyoxyethylene (2) isastearys ether (2 mole
ethoxylate ofisostearyl alcohol)], a non-ionic monomolecu
lar organic surface film as mosquito control agent was first
proposed by Garrettt and White3. Since then, this compound
had been successfully tested against various species of
mosquitoes belonging to genera Culex,Anopheles, Aedes,
Psorophora and Uranotaenia both in the laboratory and
i.i9,22-26 伽ble 1). The persistence of this com
pound is reported to range between 2 and 10 days at normal
78
application rate of 4.67 1/hectare and application at fort
nightly intervals prevented emergence of adult mosquitoes27.
When tested under simulated field conditions and in the field,
Arosurf^MSF was found to be effective for 2-12 weeks at
the application rate of 11.2 1/hectare25. Physical evaluation
of persistence of Arosui^MSF have indicated that it is
feasible to use Arosur^MSF or Arosur^MSF-alcohol for
mulations to control mosquito larvae and pupae at low
ambient temperatures12.
ArosuriPMSF can disrupt the normal orientation of
immature mosquitoes at the air-water interface by reducing
the water tension to less than 29 dynes/cm. This physical
process can kill larvae and pupae by increasing the wetting
of tracheal structures and subsequently causing anoxia (suffbcation)5,7,28. Also it can adversely affect the emergence of
adult mosquitoes3-7,22. It can also be used to entrap and drown
ovipositing females and resting males as well as sink and
inhibit the eclosen of floating eggs and egg rafts3,9.
Fourth instar larvae and pupae were significantly more
sensitive than earlier instars to the monomolecular surface
films1,5,7,9,22,25,29. Wbrk on the comparative sensitivity of
second and fourth instar larvae of Anopheles stephensi to
low dissolved oxygen levels suggested that size differences
(surface to volume ratio) are relatively important in deter
mining the survival time of submerged larvae30. Cuticular
respiration and air storage within the tracheal system enable
larvae to survive to the effect of the film. The factor respon
sible for comparatively high sensitivity of pupae to ISA-20E
was the inability of the pupae to carry on cuticular respiration5-31. Fourth instar 'larvae of An. stephensi were more
susceptible to monofilms than the fourth instars of Cx.
quinquefasciatus and Ae. aegypti25. There were high daily
mortality of the fourth instar larvae of An. arabiensis with
no adult emergence from Arosurf^MSF treated plots in rice
fields compared to lower mortality and continued adult
emergence from untreated plots, indicating the potential of
the monolayer for controlling adult emergence of
*
anophelines
29. Fourth instar larvae of Culexspp. were able
to obtain oxygen from the water for extended periods with
out contact with the water surface. On the other hand,
Anopheles larvae were more sensitive to reduced surface
tension of the water. This might be due to the structural
differences between Culex and Anopheles. In Anopheles
larvae, the dorsal palmate and filamentous setae are larger,
more numerous, situated in different locations and dif
ferentially arranged10. The high mortality of fourth instars
rather than the earlier instars is advantageous in preventing
over compensation in such a habitat where natural mortality
may be density dependent as reported by Service32.
Besides physical action, ArosurPMSF was found to
cause morphogenetic abnormalities in the treated larvae and
pupae. The effect was well marked in fourth instar larvae
and pupae. Dead pupae from larvae treated with
Arosurf^MSF as well as the late instar larvae treated in
earlier stages were often found to be deformed and
dechitinized. The morphogenetically abnormal pupae were
generally found stretched out exhibiting anomalous pos
tures. Emerging adults from surviving pupae were mostly
trapped in different phases on the water sur^ce and finally
drowned, The most common abnormality noticed was that
of a partly enclosed adult with its legs, wings and the distal
half of the abdomen trapped in the pupal skin25,31,33.
ArosurFMSF was also found to affect the ovipositional
behaviour of the female mosquitoes. It was reported that all
females which attempted to deposit eggs on the water surface
treated with Arosurf^MSF were invariably trapped before
they were -able to lay the eggs. These females could not
remain buoyant any longer and were eventually drowned.
This phenomenon continued uninterruptedly for 14 days25.
Monox Cl-FCM
Monox Cl-FCM (15% w/v suspension of insoluble
surfactant in water) is a monomolecular layer forming agent.
Successful control of larvae and pupae of Cx.
quinquefasciatus was obtained with this compound vdien
applied at the application rate of 1.89 1/m2 of 1 per cent
solution. The efficacy of this compound was more pro
nounced in septic tanks than cesspits due to the transient
nature of the pits34.
Xanthan gum
Xanthan gum, a product of plant origin is a potential
mosquito control agent. It was tested against Aedes
atropalpus pupae. The El” and LT^ were 6.18 g/m2 and
14.2 min. respectively. When Xanthan gum was applied at
the rate of22.47 g/m2, water depth had no effect on the rate
of pupal mortality. The surface layer created by Xanthan
gum prevented pupae to access the air-water interface. It did
not significantly decrease the levels of dissolved oxygen in
the test pans35.
Arosurf^MSF and larvicide/biocide mixtures
Levy et aZ11"13 and Burgess et a/14 have indicated tiiat
formulations ofArosuriPMSF and commercial preparations
of Bacillus thuringiensis var israelensis or Abate^ 4-E
(lemephos) could significantly improve the mosquito con
trolling efficacy when compared to the formulation compo
nents mainly because of delayed larvicidal and rapid
pupicidal actions of the monomolecular sur&ce film and its
persistence at recommended application rates for 2-10 days
post-treatment. ArosurPNifSF could be used along with
Gambusia affinis as a joint chemical-biological control
system and it was compatible with B. thuringiensis var
israelensis and B. sphaericus}3aA. Higi moitality in all the
stages of An. albimanus and An. stephensi resulted 讪en
79
Arosurf^MSF and Teknar were blended15. The studies of
Levy et alw have indicated that the incorporation ofalcohol
solvents with Arosurf^MSF resumed in significant increase
in larvicidal activity in 24 hours when compared to
ArosurPMSF alone. Successful control of Culex
nigripalpus, Psorophora Columbia Dyar and Knab and
Aedes taeniorhynchus Wiedemann breeding in roadside
ditches and flooded fields was resulted when Arosurf^MSF
and Abate 4-E mixture was applied at the rate of 5-6 gal/
acre indicated that the ArosurFMSF induced surface
spreading of Abate 4-E throughout the habitat prior to
solubilization12.
Table II. Efficacy of water-base mixture of Arosurf MSF
and IGRs against Culex quinquefasciatus in different
breeding habitats.
Water base
mixture
Application rate
Arosurf
IGR
(1/ha)
[Kg(ai)/ha]
Effective duration
(days)
Mixture IGR
Cesspits
*-Arosurf
OMS 3009
5.6
0.2
9
6
*-Arosurf
OMS 3013
5.6
0.2
9
3
ArosurffOMS 2015
5.6
0.2
8
2
ArosurfF
S 21149
5.6
0.2
5
2
*-Arosurf
Diflubenzuron
5.6
0.2
3
4
ArosurftMetlioprene
5.6
0.2
23
6
Resistant Development in Target Organisms to
Monomolecular Layers
Continuous challenges tests against laboratory reared
Cx. quinquefasciatus Say with ISA-20E for 15 generations
did not result in decrease in susceptibility to this surface film.
It should also be noted that more than two years of continu
ous selection pressure did not induce resistance in Cx.
quinquefasciatus to three types of petroleum hydrocar
bons36. Since ISA-20E resists oxidative rancidity; storage or
shelflife at typical ambient temperature (21-49°C) encoun
tered in many tropical and subtropical areas will not pose
any problem36.
Effect on Non-Target Organisms and Environment
Cement tanks
ArosurfF
OMS 3009
5.6
0.2
17
7
*-Arosurf
OMS 3013
5.6
0.2
43
45
*-Arosurf
OMS 2015
5.6
0.2
9
11
*-Arosurf
S 21149
5.6
0.2
13
14
ArosurPDiflubenzuron
5.6
0.2
18
20
Arosurf^
Methoprene
5.6
0.2
17
7
VCRC unpublished data
IGRs — insect growth regulators
80
Results of the field trials of mixture of ArosurFMSF
and insect growth regulators (IGRs) against unmatures of
Cx. quinquefasciatus indicated that ArosurF^MSFmethoprene mixture gave 80-100 per cent reduction in adult
emergence for 23 and 17 days in cesspits and cement tanks
respectively; whereas methoprene. alone was effective for
only one week in both cesspits and cement tanks. Similarly,
significant increase in the efficacy of OMS 3009,
OMS 3013, OMS 2015 and S 21149 was obtained in
cesspits when combined with ArosurPMSF. With respect to
OMS 3013, OMS 2015, S-21149 and diflubenzuran,
ArosurFMSF has not shown any significant impact in ce
ment tanks (Table II) (VCRC unpublished data).
Arosurf^MSF applied on an operational basis at recom
mended application rate was not found to be detrimental to
a majority of the non-target organisms」*」捋口七近刀但址。
III). Field and laboratory tests indicated that predation and
asexual reproduction of the mosquito planarian Dugesia
dorotocephala and the infectivity and development of the
mosquito nematode Romnomermis culicivorax Ross and
Smith were not afiected by ISA-20E at surface dosage of
3-4.51/hectare. This compound was also compatible with G.
affinis. Adult dragon flies were observed to oviposit in water
treated with ISA-20E7. Takahashi et alA found no adverse
eSect of ISA-20E on may fly naiads (Callibaetis spp.),
chironomid larvae and copepods
*,
at dosage of 2.5-10 1/
hectare. However, they reported iportality in corixids
(Corisella spp.)> notonectids (Notonecta unifasciata)y clam
shrimp (Eulimnadia spp.), and beetle adults (Tropisterus
lateralis). Frogs and fishes survived4 when ISA-20E was
applied at 0.68 ml/m2. ArosurFMSF when applied at the
maximum recommended dosage of 4.67 Vhectare27 did not
affect the population of zooplanktons26. However, these
studies did not consider all aquatic insects/organisms. Since
these compounds kill by physical chocking, they might have
killed many other organisms of the food chain； especially
those which rely on air-water interface for respiration.
Table IH List of non-target organisms on which the monomolccular surface film ISA-20E showed no detri
mental effect at the recommended application rates.
Species
Source
Application
rate(l/ha)
Frogs, gerrids, nymphs
of Odonata,
Ephemeroptera, aquatic
species of Coleoptera
0.41
Copepods, ostracods,
may fly naiads .
(Callipaetis- pacificus),
diving beetle adult
(Berosus metallliceps)
6.9-9.43
Green tree frog
(Hyla cinerea), fresh
water fishes (Gambusia
affinis, Hypostomus
plecostomus), saline
water fishes (Fundulus
confluentus, F. grandis,
Cyperinodon variegatus,
Poecilia latipinna,
Dormitator maculatus)
6.4
May fly naiads
(Callibaetis ,spp.)»
chironomid larve,
copepods
2.5-10
Zooplanktons
4.7
White & Garrett
with insecticides and insect pathogens, they increase their
persistence on the water surface thereby reduce their faster
solubilization and degradation. There is a remote chance of
resistant development in target species owing to their physi
cal action. However, since non-ionic surfactants with
bioactivity .similar to endogenous estrogen, are known to
affect development and sexual maturation ofvertebrates and
are implicated as cancer promoters, these non-ionic
monofilms should be evaluated for estrogenity before their
large-scale42 use in the control of vector mosquitoes.
References:
(1”7)2
1.
Mulla, M.S., Darwazeh, H.A. and Luno, L.L. Monolayer
films as mosquito control agents and their effects on nontarget
organisms. Mosq News 43: 489, 1983.
Mulla et al
*
(1983)
2.
White, S.A. and Garrett, W.D. Mosquito control with monomo
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3.
Garrett, W.D. and White, S.A. Mosquito control with monomo
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4.
Takahashi, R.M., Wilder, W.H. and Miura, T. Field evalu
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5.
Levy, R., Garrett, W.D., Chizzonite, J.J. and Miller Jr. T.W.
Control of Culex spp. mosquitoes in sewage treatment systems
at southern Florida with monomolecular organic surface
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6.
Levy, R., Chizzonite, J.J., Garrett, W.D. and Miller Jr. T.W.
Control of immature mosquitoes through applied surface
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7.
Levy, R., Chizzonite, J.J., Garrett, W.D. and Miller Jr. T.W.
Ground and aerial application of a monomolecular organic
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8.
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Webber & Cochran
(1984)x
Takahashi et al
(1984)4
v
Kenny & Ruber
(1992严
Superscript numbers refer to the si.no. in the reference list
It had been reported that ISA-20E was not phytotoxic
and did not affect wildlife. The mammalian toxicity ap
peared to be low (acute oral LD^ for rats was 20,000 mg/
kg) and the agent was nonirritating to eyes and skin5,7*10.
Howevei; recent studies indicated that a number of alkyl
phenolic compounds that are derivatives of non-ionic surfac
tants exhibited estrogenic activity37. These exogenous estro
gens are known to affect development and sexual maturation
of vertebrates and are implicated as cancer promoters38^1.
Conclusion
Monomolecular surface films are promising control
agents against mosquito immatures. When applied along
10. Levy, R., Chizzonite, J.J., Garrett, W.D. and Miller Jr. T.W.
Control of larvae and pupae of Anopheles quadrimaculatus
.
and Anopheles crucians in natural paludal ponds with the
monomolecular surface film isostearyl alcohol containing two
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81
11. Levy； R., Powell,, C.M., Herdein, B.C., Garrett, W.D.-and
Miller Jr. TW Additional studies on the use of the monomolccular
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larvae and pupae. J Fla Anti Mosq Assoc 53: 100, 1982.
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.
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Efficacy of Arosurf
*
— A monomolecular surface film in control
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82
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*
MLO. J Ecq Entomol 61: 647, 1968.
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This write-up has been contributed by Dr. D. Dominic
Amalraj and Dr. P.K. Das, Vector Control Research Centre,
Pondicherry.
ABSTRACTS
Some Research Projects Completed Recently
Oncogenic viruses associated with human premalignant
and malignant conditions of uterine cervix.
The study was carried out to screen cervical smears fbr
human papillomavirus (HPV) using in situ hybridization and
detection of viral genes in premalignant and maligant cervical
tissues by dot-blot and Southern blot techniques.
Tissue samples from uterine cervical cancers (135) and
normal cervix (50) studied immunohistochemically by pcruxidase-antiperoxidase staining revealed HPV structural antigens
in 73 (54.07%) of the cervical cancer samples and 4 (8%)
normal cervix samples. The antigen distribution was focal and
uniform or in difiiise patches.
Both dot-blot and Southern blot hybridization analyses
were employed for detection of HPV-16 and HPV-18 DNA
sequences in the DNA samples extracted from normal uterine
cervix tissue, cervical cancer tissue and cervical dysplasia
samples. In dot-blot hybridization, 44 of 80 (55.5%) cervical
cancer samples, 6 of21 (28.6%) cervical dysplasia samples and
3 of 30 (10.0%) normal samples were positive fbr HPV-16
DNA. But only 3 of 50 (6%) cervix cancer samples and none
of the dysplasia and normal samples showed the presence of
HPV-18 DNA.
By Southern blot hybridization, HPV-16 DNA was de
tected in 47 of80 (58.7%) DNA samples from cervical cancer,
7 of20 (35.0%) dysplasia samples and 3 of30 (10.0%) normal
samples. HPV-18 DNA was detected in 3 of 65 (4.6%)
cervical cancer samples. CharacteristicBamHl (8 kb) and Pst
I (2.8 kb, 1.9 kb, 1.6 kb, 1.0 kb and 0.5 kb) bands were
observed in the autoradiographs of HPV-16 DNA positive
samples. The results suggest that there is an association between
HPV-16 and cervical cancer in women from Kerala.
T. 巧 ayakumar
Regional Cancer Centre
Thiruvanathapuram.
Exptession of c-erbB-2 oncoprotein as a prognostic
indicator in breast carcinoma.
The study was carried out on tissues from 50 patients with
histologically identified carcinomas of the breast to evaluate
newer prognostic factors viz. AgNOR (Silver binding nuclear
oiganising regions), amplification and expression of, proto
oncogene c-erbB-2, and vimentin expression along Wfth estro
gen and progesterone receptors (ER and PR).
A total of 27 (54%) neoplasms showed positivity fbr cerbB-2 oncoprotein with variable degrees of staining; staining
fbr vimentin were noted in 21 (42%) of the neoplasms. Twenty
(40%) and 11 (22%) of the neoplasms were positive fbr ER and
PR respectively, while 5 (10%) were positive fbr both. The
mean AgNOR count fbr malignant neoplasms was 10.46 with
a range from 5.1 to 15.10. AgNORs in these lesions frequently
exhibited lai^e clusters, small dots and small clusters arranged
around the nuclear membrane and often dispersed throughout
the nucleus.
Poorly difierennated tumours (grade III) had evidence of
intense membranous staining (70%) than well difierentiated
(grade 1 - 54.5%) or moderately difierentiated tumours (grade
II - 44<%). When subjected to AgNOR counting, these showed
a range between 10.23 (grade I), through 11.70 (grade II) to
12.45 (grade III) mean dots/nucleus. Statisdcally the histologi
cal grade and c-erbB-2 oncoprotein over expression were
significantly correlated but not the histological grade and
AgNOR count.
,Of the 27 c-erbB-2 positive neoplasms, 21 were negative
fbr ER, 18 for PR, and 17 fbr both ER and PR of which 7 were
grade III tumours. c-erbB-2 oncoprotein over expression was
fbund to be significantly correlated to ER and PR negativity.
Staining fbr vimentin showed positivity in 21 of 50 (42%)
invasive ductal carcinomas. A total of 16 tumours showed
positivity for both vimentin and c-erbB-2 of which 7 tumours
were negative fbr ER and PR (4 were of grade III). Vimentin
was expressed in 90 per cent of grade III tumours compared to
33.3 per cent of grade I tumours. The tumours showing ER and
PR positivity did not express vimentin. Nine tumours were
negative fbr ER and PR but showed vimentin expression in
cytoplasm. The expression of vimentin in ER and PR negative
tumours was statistically significant.
It is thus concluded that c-erbB-2 marker can be used to
predict disease progression in ER and PR negative tumours.
Vimentin and c-erbB-2 oncoprotein help in detection oftumours
which do not respond to routine management. However,
AgNOR counts, c-erbB-2 oncoprotein and histologic grade did
not show much correlation. Thus AgNOR alone cannot be taken
as a marker of tumour proliferation.
C.N. Srinivas
M. Madhavan
Department of Pathology
Dr. A.L. Mudaliar
Postgraduate Institute of
Basic Medical Sciences
Madras.
83
85TH ANNIVERSARY CELEBRATIONS OF THE COUNCIL
The National Institute of Cholera and Enteric Diseases
(NICED), Calcutta, organized a one day symposium on
Cancer on Juhe 21, 1996. The symposium was attended by
the staff of the NICED, Infectious Disease Hospital and Dr.
B.C. Roy Memorial Hospital for Children of Calcutta.
The NICED, Calcutta, organised a one day symposium
on diarrhoeal diseases on July 23, 1996. The symposium
was inaugurated by Dr. Samar Roy, Director, Health Ser
vices, Government of West Bengal. Apart from several
distinguished scientists and medical experts, medical offic
ers ofthe Dr. B.C. Roy Memorial Hospital for Children, Dr.
B.C. Rpy Hospital for Crippled Children and Infectious
Diseases Hospital of Calcutta; Scientists from Institute of
Chemical Biology, Jadavpur; Bose Institute, Calcutta and
stafFmembers ofthe NICED participated in the symposium.
Dr. S.K. Bhattacharya, Director of the NICED outlined the
main achievements of the Institute since its inception in
1962.
The Regional Medical Research Centre, Bhubaneswar,
oiganised a lecture-cum-discussion programme on Health
and Nutritional Status of Mothers and Children on August
23, 1996 at the Regional Science Centre, Bhubaneswar
which was attended by youth coordinators of Nehru Yiiva
Kendra Sangathan (East zone). The Regional Medical Re
search Centre, Jabalpur, organised an awareness programme
on Environmental and Occupational Health on August 8,
1996. Stafif members from various science college of
Madhya Pradesh attending reorientation programme at the
R.D. University, Jabalpur, participated in the programme.
ICMR NEWS
The following meetings of various technical cominittees/groups of the Council were held:
Meetings of the Scientific Advisory Committees of the
ICMR Institutes/Centres:
Rajendra Memonal Research
Institute of Medical Sciences, Patna
August 21, 1996
Institute for Research in
Reproduction, Mumbai
August 28, 1996
ICMR Genetic Research Centre,
Mumbai
August 29, 1996
Enterovirus Research Centre,
Mumbai
August 29, 1996
Institute of Pathology,
New Delhi.
August 31, 1996
Meetings of the ScientiGc Advisory Committees of the
Regional Medical Research Centres:
Regional Medical Research
Centre, Dibrugarh
August 26, 1996
Regional Medical Research
Centre for Tribals, Jabalpur
August 30, 1996
Meetings of the Expert Groups (EGs)ZProject Review
Committees (PRCs) and other meetings held at New
Delhi:
EG for Preparation of Protocol
for Underaking Clinical Trials
with an Ayurvedic Medicine for
Cure of Poliomyelitis
August 14, 1996
EG to Discuss Srious Dimensions
of HIV/AIDS Vaccine in India
August 22, 1996
EG on Scientometrics Studies
August 27, 1996
National Council for Research in
Human Reproduction Sub-committee
on Reproductive Health Research
Need Assessment
August 30, 1996
\fector Control Research Centre,
Pondicheny
September 3, 1996
Centre for Research in Medical
Entomology, Madurai
September 4, 1996
PRC for Operational Research
Projects on Tuberculosis
August 31, 1996
September 13, 1996
Meeting of the Central Ethical
Committee of ICMR on Human
Research
September 10, 1996
National AIDS Research Institute
Pune
84
Participation of ICMR Scientists in ScientiHc Events:
Dr. G.B. Nair, Asstt. Director, National Institute of
Cholera and Enteric Diseases, Calcutta, participated in the
Executive Board Meeting of the International Union of
Microbiological Societies as also in the International Con
gress of Bacteriology and Applied Microbiology at Jerusa
lem (August 16-17 and 18-23, 1996 respectively).
Dr. M. Mohan Ram, Director, National Institute of
Nutrition, Hyderabad, participated in the workshop on In
stitution Building for Research and Advanced Training in
Food and Nutrition in Developing Countries at Manila
(August 18-23, 1996).
Dr. VP. Sharma, Director, Malaria Research Centre,
Delhi and Dr. B.K, lyagi Asstt. Director, Desert Medicine
Research Centre, Jodhpur, participated in the XX Interna
tional Congress of Entomology at Florence (August 25-31,
1996).
Dr. Dipika Mohanty, Director and Dr. Anita Nadkami,
Research Assistant, Institute of Immunohaematology,
Mumbai, participated in the XXVI Congress of the Interna
tional Society of Haematology at Singapore (August 25-29,
1996).
Dr. M.D. Gupte, Officer-in-Chai^e, CjlL Field Unit,
Avadi, Madras, Dr. Anil Kumai; Asstt. Director, Regional
Medical Research Centre, Bhubaneswar and Dr. K.K. Singh
and Dr. DK. Shukla, Asstt. Directors-General, ICMR Head
quarters, participated in the XIV International Scientific
Meeting of the International Epidemiological Association at
Nagoya ^August 27-30, 1996).
International Conference on Assisted Rqjroductivelechnology/Andrology 1996 at Zermatt, Switzerland (August 2931, 1996).
Dr. J.M. Deshpande, Director, Enterovirus Research
Centre, Mumbai, participated in the II meeting on Perfor
mance of Regional Vaccine Control Laboratories Network
at Jakarta (September 2-6, 1996).
Dr. Aruna Dewan, Dy. Director, National Institute of
Occupational Health, Ahmedabad, participated in the IX
meeting of the Poison Centre Working Group for the IPCS
INTOX Project at Cardiff London (Sq)tember 2-6, 1966).
Dr. V. Kumaraswami, Dy. Director, TRC, Madras,
participated in the VI meeting of the Task Force on Opera
tional Research in Filariasis ofthe WHO Special Programme
for Research at Geneva (September 9-12, 1996).
Dr. S.C. Sehgal, Director, Regional Medical Research
Centre, Port Blair, participated in the meeting of the Inter
national Leptospirosis Society at Nantes, France (September 9-12, 1996).
Dr. A. Roychaudhary, Dy. Director, Regional Occupa
tional Health Centre (Eastern), Calcutta, participated in the
XXV International Conference of Occupational Health at
Stockholm (September 15-20, 1996).
Appointments:
Dr. P.R. Narayanan took over as Director of the
Councirs Tuberculosis Research Centre, Madras w.e.f.
August 19, 1996.
Hindi Day Celebrations:
Dr. C.N. Paramasivan, Dy. Director (Senior Grade),
Tuberculosis ResearcE Centre (TRC), Madras, participated
in the XV International Working Group on Mycobacterial
Taxonomy (IWGMT) Conference on the Genus Mycobac
terium at New Castle, England (August 28-31, 1996).
Dr. Geeta Vanage, Sr. Research Officer, Institute for
Research in Reproduction, Mumbai, participated in the VII
As part of the Hindi Day Celebrations by the ICMR
Headquarters, a popular lecture (in Hindi) on ^Significance
of Post Kala-azar Dermal Leishmaniasis in Kala-azarn was
delivered on September 12, 1996 by Dr.RS. Misra, Profes
sor and Head, Department of Dermatology, Leprology and
Sexually Transmitted Diseases, Safdaijung Hospital, New
Delhi.
85
INDIAN COUNCIL OF MEDICAL RESEARCH
AWARDS AND PRIZES 1995
The Indian Council of Medical Research invites nominations/applications from Indian Scientists for its various prizes
and awards in the field of Biomedical Sciences. Application forms and other relevant information about the prizes can be
obtained from the Director-General, Indian Council of Medical Research (INDO-FOREIGN CELL), Ansari Nagar, New
Delhi-110029.
Nominations and completed applications should reach this office on or before 30th November, 1996.
1.
Basanti Devi Amir Chand Prize (Value = Rs. 5,000):
This prize will be awarded annually to a senior research worker of more than ten years standing for work of outstanding
merit in any subject in the field of biomedical science, including clinical research. The term “Clinical Research" implies
research into the mechanism and causation of disease, including its prevention and cure. The criteria for award of the prize
are the significance and value of addition to existing knowledge contributed by a worker in a particular field in which he/
she has been actively engaged over a number of years and has shown sustained activity in research.
The selection for this prize is made one year in advance.
*2. Dr.P.N.Raju Oration Award (Value = Rs.5,000):
This prize will be awarded in alternate years, to an eminent scientist, preferably a medical person, for his/her work
in any subject of national importance in the field of Medicine or Public Health. The subject will be notified at the time
of advertisement.
*3. Sandoz Oration Award for Research in Cancer (Value = Rs.2,500):
This prize (and a medal) will be awarded in alternate years, to an eminent scientist for outstanding work carried out
on a particular aspect of Cancer. The eminence is to be judged on the basis of his/her contributions to cancer research
which should have been recognised nationally and internationally and helped towards control, prevention and cure of cancer.
4.
Dr.Y.S.Narayana Rao Oration Award in Microbiology (Value = Rs.4,000):
This prize will be given in alternate years, to an eminent scientist for outstanding work carried out in the field of
Microbiology. ,The criterion for award ofthe prize is the significance and value of addition to existing knowledge contributed
by a worker in Microbiology in which he/she has been actively engaged over a number of years and has shown sustained
activity in research.
5.
Chaturvedi Kalawati Jagmohan Das Memorial Award (Value = Rs.2,000):
This prize (and a gold medal) will be awarded once in three years, to an eminent scientist, preferably a medical person,
for his/her work in the field of Cardiovascular Diseases. The criterion for award of the prize is tfie significanoe and value
of addition to existing knowledge contributed by a worker in Cardiovascular Diseases in vdiich he/she has been actively
engaged over a number of years and has shown sustained activity in research.
* This Prize/Award is not being awarded for the year 1995
86
6.
Dr.Kamala Menon Medical Research Award (Value = Rs.5,000):
This prize will be awarded to an eminent scientist, preferably a medical person, for outstanding contribution made in
the field of Internal Medicine and Paediatrics respectively in alternate years. The criterion for award of the prize is the
significance and value of addition to existing knowledge contributed by a worker on a subject in which he/she has been
actively engaged over a number of years and has shown sustained activity in research. The subject for the 1995 award is
Paediatrics.
7.
Kshanika Oration Award to a Woman Scientist for Research in the field of Biomedical Sciences
(Value = Rs.5,000):
This prize will be given annually to an eminent woman scientist for outstanding work carried out in any branch of
biomedical science, contributing to the alleviation ofhuman suffering. The criterion for award of this prize is the significance
and value of addition to existing knowledge contributed by her in any field of biomedical sciences in which she has been
actively engaged over a number of years and has shown sustained activity in research.
*8. Dr.M.K.Seshadri Prize in the field of Practice of Community Medicine (Value = Rs.10,000):
This prize (and a gold medal) will be awarded in alternate years, to an eminent scientist or institution whose original
work has led to useful inventions in or otherwise significantly contributed to the practice of Community Medicine.
9.
M.N.Sen Oration Award for Practice of Medicine (Value = Rs.5,000):
This prize will be given once in three years, to an eminent scientist for outstanding work carried out in the field ofPractice
of Medicine (clinical, laboratory or therapeutic). The criterion for award of the prize is the significance and value of
addition to existing knowledge contributed by a worker to the Practice of Medicine in xyhich he/she has been actively engaged
over a number of years and has shown sustained activity in research.
10.
JALMA Trust Fund Oration Award in the field of Leprosy (Value = Rs.5,000):
This prize (and a medal) will be given annually to an eminent scientist for outstanding research in the field of Leprosy.
The criterion for award of the prize is the significance and value of addition to existing knowledge contributed by a worker
on any aspect of leprosy in which he/she has been actively engaged over a number of years and has shown sustained activity
in research.
11.
Dr.J.B.Srivastav Award in the field of Virology (Value = Rs. 10,000):
This prize will be given in alternate years, to an eminent scientist for outstanding work carried out in the field ofVirology.
The criterion for award of the prize is the significance and value of addition to existing knowledge contributed by a worker
in Virology in which he/she has been actively engaged over a number of years and has shown sustained activity in research.
12.
ICMR Prize for Biomedical Research for Scientists belonging to Under-privileged Communities
(Value = Rs.5,000):
This prize will be given annually to an eminent scientist for his/her outstanding contributions in any field of biomedical
sciences. The criterion for award of the prize is the significance and value of addition to existing knowledge contributed
by a worker in the particular field in which he/she has been actively engaged over a number of years and has shown sustained
activity in research. This prize will be awarded to scientists belonging to under-privileged communities.
* This Prize/Award is not being awarded for the year 1995
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13.
ICMR Prize for Biomedical Research conducted in Under-developed Areas (Value = Rs.5,000):
This prize will be awarded annually to an eminent scientist for his/her outstanding contributions in any field of
Biomedical Sciences. The criterion for award of the prize is the significance and value of biomedical research carried out
by a worker based in under-developed parts of the country, or for work carried out in under-developed parts of the
country over a period of five years preceding the year for which the award is to be given.
14.
BGRC Silver Jubilee Oration Award (Value =Rs.5,000):
This prize will be given in alternate years, to an eminent scientist for outstanding work carried out in the field of
Haematology/Immunohaematology. The criterion for award of the prize is the significance and value of addition to existing
knowledge contributed by a worker in this speciality in vdiich he/she has been actively engaged over a number of years
and has shown sustained activity in research.
15.
Smt.Swaran Kanta Dingley Oration Award (Value = Rs.10,000):
This prize will be given in alternate years, to an eminent scientist for outstanding contribution in the field ofReproductive
Biology. The criterion for award of the prize is the significance and value of addition to existing knowledge contributed
by a worker in the field of Reproductive Biology in which he/she has been actively engaged over a number of years and
has shown sustained activity in research.
】6. Dr.M.O.T.Iyengar Memorial Award (Value = Rs.4,000):
This prize will be given annually to an eminent scientist for outstanding contribution in the fields of Malaria, Filariasis,
Plague or Medical Entomology. The criterion for award of the prize is the significance and value of addition to existing
knowledge contributed by a worker in any of the fields of Malaria, Filariasis, Plague or Medical Entomology in which
he/she has been actively engaged over a number of years and has shown sustained activity in research.
17.
Prof.B.K.Aikat Oration Award (Value = Rs.3,000):
This prize will be given in alternate years, to an eminent scientist for outstanding work carried out in the field ofTropical
Diseases. The criterion for award of the prize is the significance and value of addition to existing knowledge contributed
by a worker in Tropical Diseases in which he/she has been actively engaged over a number of years and has shown sustained
activity in research.
18.
Dr.Vidya Sagar Award (Value = Rs.5,000):
This prize will be awarded in alternate years, to an eminent scientist for outstanding contributions made in the field
of Mental Health. The criterion for award of the prize is the significance and value of addition to existing knowledge
contributed by a worker in Mental Health in which he/she has been actively engaged over a number ofyears and has shown
sustained activity in research.
19.
Amrut Mody-Unichem Prize (Value = Rs. 10,000):
This prize will be given to an eminent scientist for outstanding work carried out in the field of Cardiology & Neurology,
and Gastroenterology (in alternate years). The criterion for award of the prize is the significance and value of addition
to existing knowledge contributed by a worker on a subject in which he/she has been actively engaged over a number of
years and has shown sustained activity in research. The subject for the 1995 award is Gastroenterology.
8S
20.
Amrut Mody-Unichem Prize (Value = Rs. 10,000):
This prize will be given to an eminent scientist for outstanding work carried out in the field ofMatemal & Child Health,
and Chest Diseases in alternate years. The criterion for award of the prize is the significance and value of addition to
existing knowledge contributed by a worker on the subject in which he/she has been actively engaged over a number of
years and has shown sustained activity in research. The subject for the 1995 award is Maternal and Child Health.
21.
Chaturvedi Ghanshyam Das Jaigopal Memorial Award (Value = Rs.3,000):
This prize will be given in alternate years, to an eminent scientist for outstanding work carried out in the field of
Immunology. The criterion for award of the prize is the significance and value of addition to existing knowledge contributed
by a worker on the subject in which he/she has been actively engaged over a number of years and has shown sustained
activity in research.
22.
Lala Ram Chand Kandhari Award (Value = Rs.5,000):
This award will be given in alternate years, to an eminent scientist for outstanding research in the fields of Dermatology
and Sexually Transmitted Diseases. The criterion for award of the prize is the significance and value of addition to existing
contributed
*
knowledge
by a worker on the subject in which he/she has been actively engaged over a number of years and
has shown sustained activity in research.
23.
Dr.Prem Nath Wahi Award for Cytology and Preventive Oncology (Value = Rs.20,000):
This award will be given in alternate years, to an eminent scientist for outstanding contribution in the field of Basic
and/or Clinical Cytology, and/or Preventive Oncology. The criterion for award is the significance and value of addition
to existing knowledge contributed by a worker on the subject in which he/she has been actively engaged over a number
of years and has shown sustained activity in research.
24.
Dr.D.N.Prasad Memorial Oration Award (Value = Rs.20,000):
This award (and a medal) will be givqi in alternate years, to an Indian scientist fbr significant contribution to research
in the field of Pharmacology, carried out in India, as evidenced by research papers and innovations. The criteria for award
will be the significance and value of addition to existing knowledge in research in Pharmacology.
25.
ProflSurindar Mohan Marwah Award (Value = Rs.25,000):
This award will be given once in 3 years to an Indian scientist fbr significant contribution in the field of Geriatrics,
through sustained research in India on the problems of the aged as evidenced by research papers in science publications.
The subject matter could be biomedical or psychosocial research on problems of the aged, both basic and applied.
Prize/Award for Scientists above 45 years of age on January 1st of the year
for which the award is to be given
26.
Smt.Pushpa Sriramachari Award (Value = Rs.5,000):
This prize (and a silver medal) will be given in alternate years, to individuals fbr outstanding contribution to research
on "Pathology and Pathophysiology - Clinical or Experimental”. The individual should be an established scientist above
the age of 45 years and should have made a comprehensive and significant original contribution in unravelling the
understanding and the nature, evolution or prevention of any human disease entity.
89
Prizes/Awards for Young Scientists below 40 years of age on January 1st of the year for
which these awards are being given
27.
Shakuntala Amir Chand Prizes (Four in Number of Value = Rs. 1,500 each):
These four prizes will be awarded annually to the best published research work in any subject in the field ofBiomedical
Science including clinical research. The term 'Clinical Research * covers research into the mechanism and causation of
disease and its prevention and cure, and includes work on patients in hospitals, field studies in epidemiology and social
medicine, and observations in general practice.
Both medical as well as non-medical graduates are eligible for award of the prize. The prizes are awarded to Indian
nationals for work done in any institution in India. Work started in India but completed abroad will not be acceptable.
Papers published in Indian or Foreign Journals in the previous two years will be considered for award of these prizes
in the current year.
*28. Raja Ravi Sher Singh of Kalsia Memorial Cancer Research Award (Value = Rs.2,000):
This prize will be awarded in alternate years, to a scientist for outstanding work done in the Experimental or clinical
aspects of cancer or in the organisation and conduct of any service or service-cum-research programme in cancer
prevention and treatment. For the prize to be awarded in the current year the work carried out in the previous year will
be considered.
.
29.
Dr.V.N.Patwardhan Prize in Nutritional Sciences (Value = Rs.7,000):.
This prize will be given in alternate years, to an eminent scientist, for outstanding work carried out in India on
Fundamental, Clinical or Field Studies in Nutritional Sciences. The criterion fbr award of prize is the contribution of
a worker to nutritional sciences in which he/she has been actively engaged over a number of years and has shown sustained
activity in research.
30.
Tilak Venkoba Rao Award (Value = Rs.1,000):
This prize will be given to an eminent scientist fbr research in the field of Psychological Medicine and Reproductive
Physiology respectively in alternate years. The criterion fbr the award is the significance of contribution to existing
knowledge by a worker who has been actively engaged in research on the subject over a number of years. The subject for
the 1995 award is Reproductive Physiology.
31.
Dr.T.Ramachandra Rao Award (Value = Rs.3,000):
This prize will be given in alternate years, to a scientist below the age of 40 years for his/her outstanding contribution
made in the field of Medical Entomology. The criterion fbr award of the prize is the significance and value of addition
to existing knowledge contributed by a worker in this speciality in which he/she has been actively engaged over a number
of years and has shown sustained activity in research.
* This Prize/Award is not being awarded for the year 1995
90
32.
Dr.C.G.S.Iyer Oration Award (Value = Rs.1,500):
This prize will be given in alternate years, to a scientist below the age of 40 years for his/her outstanding contribution
made in the field of Leprosy. The criterion for award of the prize is the significance and value of addition to existing
knowledge contributed by a worker in this speciality in which he/she has been actively engaged over a number of years
and has shown sustained activity in research.
*33.
Dr.Dharamvir Datta Memorial Oration Award (Value = Rs.3,000):
This award will be given in alternate years, to a scientist (Medical or non-medical) below 40 years of age for work
carried out in the last 5 years in India in the field of Liver Diseases. The criteria include significance and value of addition
to existing knowledge contributed by a worker in this speciality, with special reference to application of findings to clinical
hepatology.
*34. ProfB.C.Srivastava Foundation Award (Value = Rs.5,000):
This award will be given in alternate years, to a scientist below the age of 40 years for work in the field of Community
Medicine in medical colleges/recognised institutions. The criterion for the award is the significance of research contributions
to the practice of community medicine by a worker.
35.
Smt. Kamal Satbir Award (Value = Rs.5,000):
This award will be given annually to individuals for outstanding contribution to research on Non-tuberculous Chest
Diseases, especially Respiratory Allergy and Chronic Obstructive Lung Diseases, pertaining to mechanism and
causation of the diseases, their prevention and/or management.
The work to be assessed would be the research carried out in India and published in scientific journals during the three
years preceding the year for which the award is to be given.
36.
Major General Saheb Singh Sokhey Award (Value = Rs.10,000):
This award will be given annually to a scientist below the age of 40 years for his/her outstanding contribution in the
field of Communicable Diseases depending upon its significance and value in terms of addition to existing knowledge
contributed by the worker in that field. The facets of work to be considered could be basic or applied research which add
to the knowledge on the mechanism and causation of communicable diseases, their prevention and/or their management.
The work to be assessed would be the research carried out in India and published in scientific journals, during the 3 years
preceding the year for which the award is to be given.
37.
Dr.H.B.Dingley Memorial Award (Value = Rs.5,000):
This award will be given annually to individuals for outstanding contribution to research in the field of 'Paediatrics'
by Indian scientists bSlow the age of 40 years. The woric to be assessed would be research work carried out in India and
published in scientific journals during the 3 years preceding the year for which the award is to be given.
* This Prize/Award is not being awarded for the year 1995
91
Dr. B.R.Ambedkar Centenary Award for Excellence in
Biomedical Research (Value Rs. 1.00 lakh)
Dr. B.R.Ambedkar Centenary Award for excellence in biomedical research was instituted in the year 199192 as part of the Dr. Ambedkar Birth Centenary celebrations. The award, of value Rupees one lakh, is
to be awarded in alternate years, for excellence in any field ofbiomedicai research, as evidenced by scientific
publications in internationally recognised journals, and contribution to advancement of knowledge and/or
improvements in medical practices, health programmes etc. This Award is open to all age groups.
Direct applications are not accepted for this Award. Only nominations by certain categories of people
will be considered. Details are available in a separate brochure, which are available on request
HOW TO APPLY
Applications/nominations should provide the names and other particulars of the candidates for award of the prizes to
the Council in the prescribed proforma.
Five copies (Ten copies in the case of the Basanti Devi Amir Chand Prize) of each of the following documents will
have to be sent with the application:-
1.
The proforma for application/nomination with the details duly completed.
2.
A note giving full details of the outstanding research contribution of the nominee or applicant which makes him/
her worthy of the award.
3.
A short biographical sketch of the candidate.
4.
A list of papers published by the candidate giving details ofthose published in Indian and Foreign Journals separately,
and also indicating whether the journals are indexed or not.
5.
Five reprints each of five recent significant papers published on the subject of the award by the applicant/ncfminee
(for the Basanti Devi Amir Chand Priie, ten reprints of each paper are required).
The applications for Shakuntala Amir Chand Prize should be sent along with ten copies each of the following
documents.
1.
The proforma for application/nomination with the details duly completed.
2.
Reprints of the papers submitted fbr the prize.
3.
A note giving details of research work done by the candidate.
4.
A list of papers published giving details of those published in Indian and Foreign Journals separately, and also
indicating whether the journals are indexed or not.
5.
A short biographical sketch of.the candidate.
Nomination for Dr.B.R.Ambedkar Centenary Award for Excellence in Bio-Medical Research should
be in the separate format prescribed. Direct applications will not be entertained fbr this Award.
92
TERMS & CONDITIONS OF ICMR AWARDS/PRIZES
1.
Only work published in Scientific (scholarly) Journals will be considered for ICMR Awards.
2.
Normally work done during the preceding five years on the subject will be considered (except where otherwise
indicated, under "Detailed information on the ICMR prizesZawardsn.
3.
If a scientist has received an ICMR award for a particular subject, the same material will iwt be considered for
another ICMR award or the same award in a subsequent year, unless there is evidence that additional work have
been done. As such, those applicants/nominees who have received an ICMR award previously, should clearly
indicate the additional work done by them and substantiate tiie same witii reprints of subsequent publicatiois.
4.
Only applications/nominations which are complete in all respects will be considered. Five sets of documents (10
in case of Bas anti Devi and Shakuntala Amir Chand Prizes) should be submitted, each set containing one
copy of the documents indicated in the Section “How to Apply”. If sets received are not complete, the
application/nomination will not be considered.
5.
Applicants/nominees need not provide <cNo Objection Certificates'' from co-authors (since 1990 onwards).
However in the event of any dispute, the onus will be on the applicant/nominee/recipient of an ICMR Award
or Prize, and the ICMR will not be responsible for any such dispute arising out of counter claims.
6.
The nominations/applications complete in all respects and with all the required documents should reach the Council
not later than 30th November,1996, for ICMR Awards/Prizes for the year 1995.
JOINT APPLICATIONS
In the case of joint applications/publications, the prizes shall be divided between the applicants/authors in such
proportion as the Selection Board may decide. The role of the individual who applies for the prize should be clearly
indicated so as to make it easy to determine whether major part of the work has been done by that person. A certificate
from the Senior Author that the candidate applying for the award has himselfiQierself made significant contribution to the
research work for which his/her paper is being recommended for the award should
*
also be submitted along with the
application.
FORMAT FOR FURNISHING RELEVANT INFORMATION
ABOUT THE NOMINEE/APPLICANT
Name of Award Applied for
；____________________
1.
Name of the Nominee/Applicant:
2.
Date of birth and age as on 1st January of the year for which the award is being applied for
3.
Academic qualifications beginning with the Bachelor's degree
4.
Present employment and posts held previously
5.
Details of outstanding research achievements during the last five years
6.
Whether the achievements have been recognised/awarded by any learned Society/Institution
7.
Number of scientific papers published, and reprints of those papers to be considered for the present application
93
8.
Subject of research work presented for the award
9.
Whether you have received earlier any award for tl.e same work or paper. If so: (i) Name (ii) Year (iii) A^lue of award
and (iv) Exact caption of work for which the prize was awarded
10.
Give names and designations of all the joint authors, if any, on the work/paper(s) submitted for the award
11.
State whether for the same work/paper(s) any of the joint authors have received any award. If so, give the names of
all the authors, the name of the prize awarded, year of award and its value
12.
If you are a joint author, state precisely what has been your individual contribution to the work
13.
State whether you have applied for any other award for the same or any other work. If so, state the name of die award
and the subject of work submitted for the award
14.
(i) List of papers, if any, submitted earlier for any other award and
(ii) List of papers published subsequentfy and now submitted for consideration of the award:
15.
Address for correspondence:(Please also give telephone, fax and e-mail numbers)
NOTE: Applicants for the the ICMR Prize for Biomedical Research for Scientists belonging to Underprivileged
Communities should provide attested Caste/Community Certificates.
ICMR AIDED SYMPOSIA/SEMINARS/WORKSHOPS/COURSES/CONFERENCES
Symposium/ScminarAVorkshop/
Cou rse/Co nfcrencc
Date & Place
Contact Address
Workshop on Design and Evaluation of Targeted Drug
Delivery System.
September, 1996;
(at Manipal)
Dr. N. Udupa, Convenor of the Workshop, College
of Pharmaceutical Sciences, Manipal-576119.
September 2-4, 1996;
(at Varanasi)
Dr. Yamini B. Tripathi, Organising Secretary
of the Seminar, Department of Medicinal
Chemistry, Institute of Medical Sciences,
Varanasi-221005.
National Training on Modem Technologies for Informa
tion Handling.
September 16-20, 1996:
(at New Delhi)
Dr. R.P. Kumar, Coordinator of the Training Pro
gramme, B.B. Dixit Library, All India Institute of
Medical Sciences, New Delhi-110029.
XX National Congress of Indian Association of Medical
Microbiologists.
October 31 November 3, 1996;
(at Agra)
Dr. V.M. Katoch, Organising Secretary of the
Congress, Department of Microbiology, Central
Jalma Institute for Leprosy, Agra-282001.
Symposium on Arid Ecosystem of Thar Desert of
Rajasthan and Evolutionary Ecology and Logic of Life.
November 1-3, 1996;
(at Jodhpur)
Dr. A.R. Reddy, Convenor of the Symposium,
Defence Laboratory, Jodhpur-342011.
November 4-9, 1996;
(at Nauni-Solan)
Dr. P.L. Gautam, Organising Secretary, Dr. Y.S.
Parmar University of Horticulture and Forestiy,
Nauni-Solan-173230.
Second Asian and Oceanic Congress of Andrology.
November 16-20, 1996;
(at Chandigarh)
Dr. N.R. Kalla, Chainnan of Organising Commi
ttee of the Congress, Department of Biophysics,
Panjab University, Chandigarh-160014.
XX National Conference of the Indian
Surgery of Hand.
December 7-8, 1996;
(at Agra)
Dr. S. Husain> Organising Secretary of the Con
ference, Department of Plastic and Reconstruct
*
ive Surgery, Central Jalma Institute for Leprosy,
Agra-282001.
、・、
International Seminar on
Diseases and Ayurveda.
International Workshop
Plants.
94
on
Free Radicals
Prospects
Mediated
of Medicinal
Society for
COUNCIL'S TRAINING PROGRAMMES
Leprosy
Occupational Health
At the Central Jalma Institute for Leprosy, Agra:
At the National Institute of Occupational Health,
Ahmedabad:
•
Multidrug Therapy Orientation Course in Leprosy for
Medical Officers (September 9-20, 1996).
Reproductive Biology
Training Course on Current Trends in Management of
Infertility and Reproductive Disorders (September 213, 1996).
Nutrition
At the National Centre for Laboratory Animal Science,
National Institute of Nutrition, Hyderabad:
•
Training Course fbr Laboratory Animal Supervisors
(September 2-November 29, 1996).
Haematology
At the National Institute of Nutrition, Hyderabad:
•
Orientation Course on Occupational Health fbr Indus
trial Medical Officers (September 17-29, 1996).
Laboratory Animal Technology
At the Institute for Research in Reproduction, Mumbai:
•
•
Annual Training Course in Nutrition (December 1,
1996-Febniary 28, 1997).
At the Institute of Immunohaematology, Mumbai:
•
Training Course in Advanced Haematology and
Immunohaematology (September 17-October4,1996).
ICMR PUBLICATIONS
Price (Rs.)
Nutritive X^lue of Indian Foods (1985), by C. Gopalan, B.V Ramasastri and
S.C. Balasubramaniam, Revised and Updated (1989), by B.S. Narasinga Rao, K.C. Pant
and Y.G. Deosthale (Reprinted 1995)
23.00
Growth & Physical Development of Indian Infants and Children (1972, Reprinted 1989)
10.00
Studies on Weaning & Supplementary Foods (1974, Reprinted 1996)
15.00
Studies on Pre-School Children (1974, Reprinted 1984)
6.00
A Manual of Nutrition (Second Edition 1974, Reprinted 1995)
6.00
Low Cost Nutritious Supplements (Second Edition 1975, Reprinted 1994)
4.00
Menus for Low Cost Balanced Diets and School Lunch Programmes Suitable for
North India (Second Edition 1977, Reprinted. 1994)
4.50
Some Common Indian Recipes and their Nutritive Value (Fourth Edition 1977,
Reprinted 1995) by S waran Pasricha & L.M. Rebello
10.00
Nutrition for Mother & Child (Third Edition 1978, Reprinted 1994) by P.S.
Venkatachalam & L.M. Rebello
9.00
X
-- ------ V
library
AHO
"
:或
> CA
Japanese Encephalitis in India (Revised Edition 1980)
5.00
Some Therapeutic Diets (Fourth Edition 1988, Reprinted 1995) by Swaran Pasricha
4.50
Nutrient Requirements & Recommended Dietary Allowances for Indians (1990, Reprinted 1995) 16.00
Count What 'Ybu Eat (1989, Reprinted 1994) by Swaran Pasricha
9.00
Diet & Diabetes (Second Edition 1993) by T.C. Raghuram, Swaran Pasricha & R.D. Sharma
18.00
Dietary Tips for the Elderly (1992) by Swaran Pasricha & B.V.S. Thimmayamma
3.50
Diet and Heart Disease (1994, Reprinted 1996) by Ghafborunissa and Kamala Krishnaswamy
26.00
♦Depressive Disease (1986) by A. Venkoba Rao
58.00
♦♦Medicinal Plants of India Vol.2 (1987)
136.00
* 10 per cent discount allowed to individuals.
*
♦
25 per cent discount allowed to individuals.
These publications are available on prepayment of cost by cheque, bank draft or postal order (bank and postal charges
will be extra) in favour of the Director-General, Indian Council of Medical Research, New Delhi. Money orders are not
acceptable. All correspondence in this regard should be addressed to the Chief, Division of Publication and Information,
Indian Council of Medical Research, Post Box No.4911, Ansari Nagar, New Delhi-110029 (India).
INDIAN COUNCIL OF MEDICAL RESEARCH
Grant-in-aid for organising Seminars/Symposia/Workshops
The Council provides partial financial assistance for organising Seminars/SymposiaAVorkshops.
Applications for grant of financial assistance (complete in all respects in the prescribed proforma), will be
considered only if furnished at least four months before the date of commencement of the Seminar/
Symposium/Workshop, etc.
EDITORIAL BOARD
Dr. G.V. Satyavati
Chairperson
Dr. Badri N. Saxena
Dr. Bela Shah
.・
Dr. N. Medappa
..Editor
Member
Member
-
Printed and Published by Shri J.N. Mathur for the Indian Council of Medical Research, New Delhi
at the ICMR Offset Press, New Delhi-110029
R.N. 21813/71
•
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